Hardy-Weinberg equilibrium

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A brief description:

This tool allows examining the compliance between observed and expected number of genotypes based on Hardy-Weinberg law. The users insert numbers of homozygous, heterozygous and rare homozygous individuals and the significance level - alfa. Output values are the expected number of individuals, frequencies of "p" and "q" alleles, p-value, chi-square value and brief information about the significance of results. When the study group is not in a state of genetic equilibrium (p ≤ alfa) application will count Fis value to estimate the reason of disturbance. If observed number of individuals in one of the cells is smaller then 5, application will count additionally chi-square and p-value with Yate`s correction for continuity in this case status of results will be determined on the basis of these values. 

More information in Materials & Methods

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